Endocrine Abstracts

Introduction: The glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzyme deficiency in humans. In red blood cells, the pentose phosphate pathway is the only source of nicotinamide adenine dinucleotide (NADPH), and defense mechanisms against oxidative damage are highly dependent on G6PD activity. The occurrence of acute haemolysis in patient with G6PD deficiency and diabetes has been reported and ascribed to various mechanisms. Her we report a case of pat...

Introduction: Obesity exposes to multiple complications, including cardiovascular and metabolic ones. It can also cause respiratory problems, which are still insufficiently researched. The objective of this study was to detect respiratory abnormalities in a group of obese people followed in an obesity unit.Methods: This was a descriptive and analytical cross-sectional study of 100 obese patients consulting at the human obesity research unit of the Nation...

Introduction: Diabetes is the cause of ophthalmological complications that are all the more severe when the balance of diabetes is precarious. Among the non-retinal ocular targets of diabetes is damage to the optic nerve. The diagnosis of diabetic mononeuritis should only be made after excluding other causes of neuropathy.Observation: We report the case of a patient referred to our service for equilibration of diabetes. This is a 59-year-old patient, typ...

Introduction: The diabetic foot is a frequent, serious and costly complication of diabetes. The prevention of diabetic foot involves a systematic podiatric evaluation of diabetic patients to identify the foot at risk. The aim of our study was to determine the podiatric risk in a Tunisian diabetic population according to the classification of the International Working Group on the Diabetic Foot (IWGDF) and the factors associated with podiatric risk.Method...

Introduction: Diabetes mellitus (DM) is the most common endocrine disorder. The skin manifestations of diabetes can vary depending on the duration of the disease and the control of blood glucose levels. Almost all patients with DM eventually develop skin changes due to the long-term effects of hyperglycemia on microcirculation and skin collagen. This study was conducted to find the hospital based prevalence of mucocutaneous manifestations in patients with diabetes mellitus, th...

Introduction: Olive oil is the most representative food of the traditional Mediterranean Diet (MedDiet) that, besides having high-monounsaturated fatty acids content, contains other minor components with biological properties. Olive oil as a food, and the MedDiet as a food pattern are associated with a decreased risk of cardiovascular disease, obesity and diabetes mellitus. The aim of this study was to determine the relationship between adherence to the Mediterranean Diet and ...

Introduction: The progressive increase in diabetes is likely to increase the incidence of amputations. Despite a wealth of research highlighting the importance of early detection and management, prevention practices remain poor, with inconsistent patient follow-up and compliance. The aim of our study was to assess the prevalence and risk factors for lower limb amputation in a third-line hospital among diabetics.Methods: It was a retrospective study inclu...

Introduction: Insulin therapy remains a treatment of last resort for type 2 diabetic patients with uncontrolled diabetes with oral antidiabetic. The aim of this study was to find a correlation between the initial dose of insulin and the glycated hemoglobin (A1c) level.Methods: We conducted a cross sectional study. We included 63 patients with type 2 diabetes hospitalized for a switching to insulin in the C department of diabetology and nutrition at the N...

Introduction: Obesity is the disease of modern society whose prevalence continues to increase.The aim of this study was to compare the cardio-metabolic profile of morbid obesity with that of moderate to severe obesity.Methods: It was a retrospective study conducted at the obesity unit of the national institute of nutrition in Tunis including 174 obese patients We divided the population into two groups. Group 1 (G1) with morbid obes...